Micro flow cytometer with self-aligned 3D hydrodynamic focusing
نویسندگان
چکیده
منابع مشابه
Hydrodynamic Focusing for a Micromachined Flow Cytometer
This paper describes hydrodynamic focusing inside a micromachined flow cytometer. Flow cytometry is a process whereby cells are analyzed and sorted based on hydrodynamic focusing phenomenon and specific cellular characteristics. In this study, the hydrodynamic focusing phenomenon is first modeled by employing potential flow theory. Then the flow field inside the flow cytometer is numerically si...
متن کاملSingle-layer planar on-chip flow cytometer using microfluidic drifting based three-dimensional (3D) hydrodynamic focusing.
In this work, we demonstrate an on-chip microfluidic flow cytometry system based on a three-dimensional (3D) hydrodynamic focusing technique, microfluidic drifting. By inducing Dean flow in a curved microfluidic channel, microfluidic drifting can be used to hydrodynamically focus cells or particles in the vertical direction and enables the 3D hydrodynamic focusing in a single-layer planar micro...
متن کاملSingle channel layer, single sheath-flow inlet microfluidic flow cytometer with three-dimensional hydrodynamic focusing.
Flow cytometry is a technique capable of optically characterizing biological particles in a high-throughput manner. In flow cytometry, three dimensional (3D) hydrodynamic focusing is critical for accurate and consistent measurements. Due to the advantages of microfluidic techniques, a number of microfluidic flow cytometers with 3D hydrodynamic focusing have been developed in recent decades. How...
متن کاملSimplified Monolithic Flow Cytometer Chip with Three-dimensional Hydrodynamic Focusing and Integrated Fiber-free Optics
A miniaturized flow cytometry incorporating both fluidic and optical systems has a great possibility for portable biochemical sensing or point-of-care diagnostics. This paper presents a simple microfluidic flow cytometer combining reliable 3D hydrodynamic focusing and optical detection without optical fibers in a monolithic architecture fabricated by a single photolithographic process. The vert...
متن کاملLow cost Micro-Coulter counter with hydrodynamic focusing
We report on the fabrication and characterization of a low-cost micro-Coulter counter fabricated from biocompatible materials (Poly-dimethylsiloxane, glass and gold) and incorporating hydrodynamic focusing. The developed micro-Coulter counter offers a low-cost alternative to equivalent existing devices and, thanks to the hydrodynamic focusing, provides high versatility, being able to probe part...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2014
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.6.000054